Thermo Fisher Scientific EIF2B3 Monoclonal Antibody (OTI2D2), TrueMAB
EIF2B3 단백질을 인식하는 Mouse monoclonal 항체로, Western blot 및 Immunocytochemistry에 적합. HEK293T 세포에서 생산된 full-length human EIF2B3 단백질로 면역화됨. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D2 |
| Immunogen | Full-length human recombinant EIF2B3 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
Mutations in any of the five subunits of eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter.
EIF2B3 also functions as a cofactor in hepatitis C virus internal ribosome entry site-mediated translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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