Thermo Fisher Scientific LC3B Polyclonal Antibody
LC3B 단백질을 인식하는 Thermo Fisher Scientific의 Sheep Polyclonal Antibody. Western blot 및 IHC에 사용 가능. 인간 LC3B 오토파지 마커 연구용으로 적합. 동결건조 형태로 제공되며, 연구 전용 제품.
- 카탈로그번호
- OSM00027W
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:200–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human LC3B conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10982471 |
Product Specific Information
Reconstitute with 150 µL of distilled water.
Target Information
LC3B (Autophagy Marker Light Chain 3B, MAP1A/MAP1B LC3B) in humans is encoded by the gene MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B).
LC3B is associated with microtubule assembly and plays an important role in neurogenesis and autophagy — a process involving degradation of cytoplasmic components.
Three LC3 isoforms undergo post-translational modifications during autophagy. Macroautophagy is the major inducible pathway for turnover of cytoplasmic constituents in eukaryotic cells, responsible for degradation of enzymes and organelles during nutrient starvation.
LC3B mediates interactions between microtubules and cytoskeletal components and may be involved in cancer, aging, metabolic and neurodegenerative disorders, and cardiovascular/pulmonary diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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