Thermo Fisher Scientific LIPC Polyclonal Antibody
LIPC 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 적합. Human, Mouse, Rat 반응성. Affinity chromatography로 정제된 액상 시약이며, PBS/glycerol buffer에 보존. 내인성 LIPC 단백질 검출에 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LIPC (Accession P11150), corresponding to amino acid residues R281–E331 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851816 |
Product Specific Information
Antibody detects endogenous levels of total LIPC.
Target Information
The Lipase family belongs to one of the most robust genetic superfamilies found in living organisms, including esterases and thioesterases. Lipase gene products are related by tertiary structure rather than primary amino acid sequence. Balancing the composition and transport of lipoproteins in human plasma is essential for normal body function and is mediated in part by Hepatic Lipase (HL, LIPC).
Rare deficiencies in Hepatic Lipase can lead to abnormal levels of circulating lipoprotein particles, associated with coronary artery disease (CAD). Hepatic Lipase is regulated by thyroid hormones and functions both as a triglyceride hydrolase and as a ligand/bridging factor for receptor-mediated lipoprotein uptake. It localizes to the endothelial surfaces of extrahepatic tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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