Thermo Fisher Scientific HFE Polyclonal Antibody
HFE 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 마우스, 랫트에 반응하며, 고순도 Affinity chromatography로 정제됨. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HFE (Accession Q30201), corresponding to amino acid residues Q119–W169 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851813 |
Product Specific Information
Antibody detects endogenous levels of total HFE.
Target Information
The protein encoded by this gene is a membrane protein similar to MHC class I-type proteins and associates with beta2-microglobulin. It regulates iron absorption by controlling the interaction between the transferrin receptor and transferrin. Mutations in this gene cause hereditary haemochromatosis, a recessive iron storage disorder. At least nine alternatively spliced variants have been described, with additional variants identified but not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-102408_HFE_Q30201-1_Rabbit.svg 및 PA5-102408_HFE_Q30201-1_Rabbit_PDP.jpeg 이미지 포함)
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