Thermo Fisher Scientific Human TRIM5 gamma Synthetic Peptide
Human TRIM5γ 합성 펩타이드로, TRIM5δ의 C-말단 15개 아미노산 서열을 포함합니다. 폴리클로날 항체 PA5-20047의 블로킹 펩타이드로 사용 가능하며, 연구용으로만 제공됩니다. 액상 형태, PBS 버퍼에 0.1% BSA 및 0.02% sodium azide 포함.
- 카탈로그번호
- PEP0166
- 카테고리
- Esters
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids from the carboxy terminus of human TRIM5δ.
PEP-0166 can be used as a blocking peptide with polyclonal antibody PA5-20047.
Target Information
TRIM5 is a member of a broad family of proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region.
TRIM5 has five alternately spliced isoforms, the longest being the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain.
While a function has not yet been assigned to TRIM5-gamma, expression of TRIM5-alpha variants from humans, rhesus monkeys, and African green monkeys enables resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies.
Furthermore, the TRIM5δ isoform appears to serve as a scaffold for the assembly of endogenous BTBD1 and BTBD2 proteins and also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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