
Thermo Fisher Scientific Semaphorin 3F Polyclonal Antibody
인간, 마우스, 랫트 반응성을 가진 Sema3F 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. KLH 결합 합성 펩타이드(aa 201–300)로 면역화된 Rabbit IgG 형태이며, 단백질 A로 정제된 액상 제품입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Sema3F (amino acids 201–300) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The semaphorins are a family of proteins involved in signaling. All members possess a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues (Kolodkin et al., 1993 [PubMed 8269517]).
Sequence comparisons have grouped the secreted semaphorins into three general classes, all containing an immunoglobulin domain.
The semaphorin III family—including human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E—features a basic domain at the C terminus.
Chicken collapsin contributes to axonal pathfinding during development by inhibiting growth cone extension (Luo et al., 1993 [PubMed 8402908]) through interaction with a collapsin response mediator protein (CRMP62) (Goshima et al., 1995 [PubMed 7637782]), a putative homolog of the UNC33 gene product (MIM 601168).
SEMA3F is a secreted member of the semaphorin III family.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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