Thermo Fisher Scientific Semaphorin 3F Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000

ELISA

• Tested Dilution: 1:500–1:1,000

Product Specifications

Target Information

The semaphorins are a family of proteins involved in signaling. All members possess a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues (Kolodkin et al., 1993 [PubMed 8269517]).
Sequence comparisons have grouped the secreted semaphorins into three general classes, all containing an immunoglobulin domain.
The semaphorin III family—including human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E—features a basic domain at the C terminus.
Chicken collapsin contributes to axonal pathfinding during development by inhibiting growth cone extension (Luo et al., 1993 [PubMed 8402908]) through interaction with a collapsin response mediator protein (CRMP62) (Goshima et al., 1995 [PubMed 7637782]), a putative homolog of the UNC33 gene product (MIM 601168).
SEMA3F is a secreted member of the semaphorin III family.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.