Thermo Fisher Scientific HRH3 Polyclonal Antibody
HRH3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며, Protein A로 정제된 액상 형태입니다. 신경전달물질 조절 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human HRH3 (amino acids 281–380) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Histamine H3 Receptor (HRH3) regulates the release of neurotransmitters such as norepinephrine and somatostatin. In histamine-containing neurons of the brain, it acts as a presynaptic autoreceptor, while in non-histamine-containing neurons, both in the central and peripheral nervous systems, it functions as a presynaptic heteroreceptor. Multiple isoforms are produced by alternative splicing. HRH3 expression is primarily observed in the brain, with ESTs identified from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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