Thermo Fisher Scientific CaMKK alpha Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human CaMKK alpha. Recombinant protein control fragment (Product #RP-95195). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CaMKK alpha,uniProtId:Q8N5S9-1,ncbiNodeId:9606,antigenRange:451-505,antigenLength:505,antigenImageFileName:PA5-110951_CaMKK_alpha_Q8N5S9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110951_CaMKK_alpha_Q8N5S9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856362

Product Specific Information

Immunogen sequence: KSMLRKRSFG NPFEPQARRE ERSMSAPGNL LVKEGFGEGG KSPELPGVQE DEAAS

Target Information

CAMKK1 (CAMKKA) is a serine/threonine protein kinase family member, and belongs to the Ca2+/calmodulin-dependent protein kinase subfamily. The product of CaMKK alpha is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. CAMKK1 functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for CaMKK alpha. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.