Thermo Fisher Scientific Coilin Polyclonal Antibody
Human Coilin 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액에 보관됩니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Coilin (Product # RP-105782) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856361 |
Product Specific Information
Immunogen sequence:
NRSTDNQRQQ QLNDVVKNSS TIIQNPVETP KKDYSLLPLL AAAPQVGEKI AFKLLELTSS YSPDVSDYKE GRILSHNPET QQVDIEILSS LPALREPGKF DLVYHNENGA EVVEYAVTQE SKITVFWKEL IDPRLIIESP SNTSSTEPA
Target Information
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies).
Cajal bodies are nuclear suborganelles involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs.
The N-terminus of the coilin protein directs self-oligomerization, while the C-terminus influences the number of nuclear bodies per cell.
Differential methylation and phosphorylation of coilin likely influence its localization among nuclear bodies and the composition and assembly of Cajal bodies.
This gene has pseudogenes on chromosome 4 and chromosome 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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