Thermo Fisher Scientific CNOT6 Polyclonal Antibody
Human CNOT6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. 보존제가 포함되지 않아 필요 시 sodium azide를 첨가할 수 있습니다. Protein A 및 항원 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the Human CNOT6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788393 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human CNOT6.
Target Information
Poly(A) nuclease with 3′–5′ RNase activity. Catalytic component of the CCR4-NOT complex, a major cellular mRNA deadenylase involved in mRNA degradation, miRNA-mediated repression, translational repression during initiation, and general transcription regulation.
Participates in mRNA decay mediated by the mCRD of the FOS gene in the cytoplasm. In the presence of ZNF335, enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA. Plays roles in cell proliferation, survival, and prevention of cellular senescence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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