Thermo Fisher Scientific Dot1L Polyclonal Antibody
Dot1L 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 핵 내 Dot1L 검출에 유용합니다. Affinity 정제된 액상 제품으로, -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1438–1537 of human Dot1L/KMT4 (NP_1158711) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.28 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804944 |
Product Specific Information
- Positive Samples: Mouse liver, Rat liver
- Cellular Location: Nucleus
Immunogen sequence:
LLSGPGLAPA ASSAGGAASS AQTHRSFLGP FPPGPQFALG PMSLQANLGS VAGSSVLQSL FSSVPAAAGL VHVSSAATRL TNSHAMGSFS GVAGGTVGGN
Target Information
Histone methyltransferase that methylates Lys-79 of histone H3.
Prefers nucleosomes as substrate compared to free histones.
Binds to DNA.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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