Thermo Fisher Scientific NKG2A Polyclonal Antibody
Thermo Fisher Scientific의 NKG2A Polyclonal Antibody는 마우스 시료에 반응하는 Rabbit IgG 기반 항체로, Western blot 및 ELISA에 적합합니다. KLRC1(aa 96–215) 재조합 단백질로 면역화되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA588485
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 96–215 of human KLRC1 (NP_0155671) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.53 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804945 |
Product Specific Information
- Immunogen sequence: RHCGHCPEEW ITYSNSCYYI GKERRTWEES LLACTSKNSS LLSIDNEEEM KFLSIISPSS WIGVFRNSSH HPWVTMNGLA FKHEIKDSDN AELNCAVLQV NRLKSAQCGS SIIYHCKHKL
- Positive Samples: Mouse testis, Mouse liver
- Cellular Location: Membrane, Single-pass type II membrane protein
Target Information
Natural killer (NK) cells are lymphocytes that mediate lysis of certain tumor and virus-infected cells without prior activation and regulate humoral and cell-mediated immunity. The encoded protein belongs to the killer cell lectin-like receptor (NKG2) family, characterized by type II membrane orientation and a C-type lectin domain. It forms a complex with KLRD1/CD94 and recognizes MHC class I HLA-E molecules in NK cells. NKG2 family genes form a receptor cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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