Thermo Fisher Scientific CHRM1 Polyclonal Antibody
CHRM1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot과 ELISA에 적합하며, 고순도 Affinity Chromatography 정제. 액상 형태로 안정적인 1.33 mg/mL 농도 유지. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 400–460 of human CHRM1 (NP_0007292) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.33 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804941 |
Product Specific Information
- Immunogen sequence: WELGYWLCYV NSTINPMCYA LCNKAFRDTF RLLLLCRWDK RRWRKIPKRP GSVHRTPSRQ C
- Positive Samples: U-87MG, HepG2
- Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Target Information
The muscarinic cholinergic receptors belong to a family of G protein-coupled receptors. Their functional diversity is defined by acetylcholine binding, which mediates cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel regulation.
Muscarinic receptors influence various effects of acetylcholine in the central and peripheral nervous systems.
CHRM1 is involved in vagally-induced bronchoconstriction and gastric acid secretion. The gene encoding this receptor is localized to chromosome 11q13.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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