Thermo Fisher Scientific RALBP1 Recombinant Rabbit Monoclonal Antibody (5C10W9)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

5C10W9

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human RALBP1 (Q15311). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RALBP1,uniProtId:Q15311-1,ncbiNodeId:9606,antigenRange:200-300,antigenLength:655,antigenImageFileName:MA5-42934_RALBP1_Q15311-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42934_RALBP1_Q15311-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.18 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912075

Product Specific Information

Positive test controls include: THP-1, C6. The target is usually found in the following locations: Membrane, Peripheral membrane protein.

Immunogen sequence: RTMMYDGIRL PAVFRECIDY VEKYGMKCEG IYRVSGIKSK VDELKAAYDR EESTNLEDYE PNTVASLLKQ YLRDLPENLL TKELMPRFEE ACGRTTETEK V

Target Information

Can specifically activate hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.