Thermo Fisher Scientific LIN28A Recombinant Rabbit Monoclonal Antibody (2S1I10)
LIN28A 단백질을 인식하는 재조합 토끼 단클론 항체로, Human, Mouse, Rat 시료에 반응합니다. ICC/IF 및 ELISA에 적합하며, 0.7 mg/mL 농도의 액상 형태로 제공됩니다. iPS 세포 연구 및 발달생물학 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2S1I10 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human LIN28A (UniProt ID: Q9H9Z2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912070 |
Product Specific Information
- Positive test controls: Mouse testis, Rat testis
- Immunogen sequence:
MGSVSNQQFA GGCAKAAEEA PEEAPEDAAR AADEPQLLHG AGICKWFNVR MGFGFLSMTA RAGVALDPPV DVFVHQSKLH MEGFRSLKEG EAVEFTFKKS
Target Information
Lin28 is a transcription factor initially identified for its role in developmental timing in C. elegans. It plays a critical role in stem cell biology and the generation of induced pluripotent stem (iPS) cells. Lin28, in combination with transcription factors such as POU5F1, Sox2, and NANOG, can reprogram somatic cells into iPS cells. This process has potential applications in regenerative medicine by avoiding viral vectors and improving safety for therapeutic use.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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