Thermo Fisher Scientific IL-6 (Interleukin-6)/Interferon beta-2 (Hybridoma Growth Factor) Monoclonal Antibody (IL6/4643)
인간 IL-6 단백질을 인식하는 마우스 단클론 항체로, 염증 반응 및 자가면역 연구에 적합. IHC(P)와 Peptide Array에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, 4°C에서 보관. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL6/4643 |
| Immunogen | Recombinant fragment (around aa1–200) of human IL-6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Human heart or adrenal gland; stimulated peritoneal macrophages
- Cellular Location: Cytoplasm; Extracellular (Secreted)
Target Information
IL-6 encodes a cytokine involved in inflammation and B cell maturation. This endogenous pyrogen induces fever and is expressed at sites of acute and chronic inflammation, activating transcriptional responses via the interleukin 6 receptor alpha.
IL-6 is implicated in multiple inflammation-related diseases, including diabetes mellitus, systemic juvenile rheumatoid arthritis, Kaposi sarcoma, and rheumatoid arthritis. Elevated IL-6 levels are also observed in viral infections such as COVID-19 (SARS-CoV-2 infection).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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