Thermo Fisher Scientific DJ-1 Polyclonal Antibody
DJ-1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, IP 등 다양한 응용에 사용 가능. 인간, 마우스, 랫, 햄스터, 어류 시료에서 검출 가능. 산화 스트레스 관련 연구 및 파킨슨병 연구에 적합. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | 1:500 | - |
| Immunoprecipitation (IP) | 1:200 | - |
| In vitro Assay (IV) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues between 150–189 of human DJ-1 (C-terminus) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1957262 |
Product Specific Information
PA1-32440 detects DJ-1 from mouse, human, rat, hamster, and fish samples.
Target Information
The DJ-1 gene encodes a protein belonging to the peptidase C56 family. It acts as a positive regulator of androgen receptor-dependent transcription and may function as a redox-sensitive chaperone and oxidative stress sensor, protecting neurons from oxidative stress-induced cell death. Mutations in this gene are associated with autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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