Thermo Fisher Scientific Phospho-FLT3 (Tyr599) Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Target Information

FLT3 is a tyrosine protein kinase belonging to the growth factor receptor tyrosine kinase family. Activation occurs upon binding of the FLT3 ligand to the extracellular domain, inducing receptor homodimerization and autophosphorylation. The activated receptor phosphorylates downstream effectors involved in apoptosis, proliferation, and differentiation of hematopoietic cells. Constitutive activation mutations are associated with acute myeloid leukemia and acute lymphoblastic leukemia.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.