Thermo Fisher Scientific Phospho-FLT3 (Tyr599) Polyclonal Antibody
인간 FLT3의 Tyr599 인산화 부위에 특이적인 rabbit polyclonal antibody. Western blot에 최적화된 시약으로 세포 신호전달 및 백혈병 관련 연구에 활용 가능. 액상 형태, 1 mg/mL 농도, -20°C 보관.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human FLT3 around the phosphorylation site of Tyr599 (Y-E-YP-D-L) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554874 |
Target Information
FLT3 is a tyrosine protein kinase belonging to the growth factor receptor tyrosine kinase family. Activation occurs upon binding of the FLT3 ligand to the extracellular domain, inducing receptor homodimerization and autophosphorylation. The activated receptor phosphorylates downstream effectors involved in apoptosis, proliferation, and differentiation of hematopoietic cells. Constitutive activation mutations are associated with acute myeloid leukemia and acute lymphoblastic leukemia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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