Thermo Fisher Scientific GFR alpha-2 Polyclonal Antibody
Rabbit polyclonal antibody against human GFR alpha-2, validated for WB and ICC/IF. Detects ~52kDa band in HeLa lysate. Supplied as unconjugated liquid at 1 mg/mL in PBS with sodium azide. Suitable for research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to amino acids 360–410 of human GFR alpha-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 2–8°C (up to 3 months); -20°C (long-term storage) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152274 |
Product Specific Information
In Western blot applications, this antibody detects a band at approximately 52 kDa.
A suggested positive control is HeLa cell lysate.
PA5-19874 can be used with blocking peptide PEP-0254.
Target Information
GFRα-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF.
NTN, GFRα-2, and RET form a complex to transduce NTN signal and mediate NTN function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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