Thermo Fisher Scientific KV3.2 (KCNC2) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human KCNC2(Accession Q96PR1), corresponding to amino acid residues G180-F230. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KV3.2 (KCNC2),uniProtId:Q96PR1-1,ncbiNodeId:9606,antigenRange:180-230,antigenLength:638,antigenImageFileName:PA5-115448_KV3.2_KCNC2_Q96PR1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-115448_KV3.2_KCNC2_Q96PR1-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2900084

Product Specific Information

Antibody detects endogenous levels of total KCNC2.

Target Information

Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels. The subunits vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha subunits, which include the KV1, KV2, KV3, KV4 and KV9 proteins, as well as accessory subunits that modify the gating properties of the coexpressed KV subunits. KV3.2 is a multipass membrane protein that regulates the voltage-dependent K+ permeability of excitable membranes. The tail of KV3.2 may be influential in the targeting of the channel to specific subcellular compartments and/or the regulation of channel activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.