Thermo Fisher Scientific KV3.2 (KCNC2) Polyclonal Antibody
Rabbit 폴리클로날 항체로 Human, Mouse, Rat의 KCNC2(KV3.2) 단백질 검출에 사용. Western blot 및 IHC(P) 검증 완료. 합성 펩타이드 면역원 사용. 액상 형태, 1 mg/mL, PBS+50% glycerol에 보관. -20°C에서 보관, 연구용 전용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KCNC2 (Accession Q96PR1), corresponding to amino acid residues G180–F230 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900084 |
Product Specific Information
Antibody detects endogenous levels of total KCNC2.
Target Information
Voltage-gated K⁺ channels in the plasma membrane control the repolarization and frequency of action potentials in neurons, muscles, and other excitable cells.
The KV gene family encodes more than 30 proteins that comprise the subunits of K⁺ channels. These subunits vary in gating and permeation properties, subcellular distribution, and expression patterns.
Functional KV channels assemble as tetramers consisting of pore-forming alpha subunits (KV1, KV2, KV3, KV4, and KV9) and accessory subunits that modify gating properties.
KV3.2 is a multipass membrane protein regulating voltage-dependent K⁺ permeability of excitable membranes. Its tail may influence channel targeting to specific subcellular compartments and/or regulation of channel activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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