Thermo Fisher Scientific KV4.1 (KCND1) Polyclonal Antibody
KCND1(KV4.1) 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunocytochemistry에 적합. Human 및 Mouse 시료 반응. Affinity chromatography로 정제된 액상 항체이며, PBS/50% glycerol buffer에 보존. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KCND1 (Accession Q9NSA2), corresponding to amino acid residues V518–S568 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900086 |
Product Specific Information
Antibody detects endogenous levels of total KCND1.
Target Information
The KV gene family encodes more than 30 genes that comprise the subunits of K⁺ channels, varying in gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers of pore-forming alpha-subunits (KVα), including KV1, KV2, KV3, and KV4 proteins, with accessory KVβ subunits that modulate gating properties. Differences in trafficking, biosynthetic processing, and surface expression of major KV1 subunits (KV1.1, KV1.2, KV1.4) in rat and human brain suggest tight regulation of subunit assembly and neuronal channel formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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