Thermo Fisher Scientific RET Monoclonal Antibody (8D10C9)
RET 단백질을 표적하는 Mouse IgG1 단클론 항체로, Human 시료에서 WB 및 ELISA에 적합합니다. 정제된 재조합 RET(aa896-1063) 항원을 면역원으로 사용하였으며, 비결합형 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8D10C9 |
| Immunogen | Purified recombinant fragment of RET (aa896–1063) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% Sodium Azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet Ice |
| RRID | AB_10981958 |
Product Specific Information
MA5-15364 targets RET in indirect ELISA and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of RET (aa896–1063) expressed in E. coli.
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. It transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia type IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma.
Two transcript variants encoding different isoforms have been found for the RET gene, with additional variants described but not confirmed for biological validity.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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