Thermo Fisher Scientific Mycobacterium tuberculosis Ag85b Polyclonal Antibody
Mycobacterium tuberculosis Ag85b 단백질을 인식하는 토끼 다클론 항체. Western blot 및 ELISA에 사용 가능하며, 친화 크로마토그래피로 정제됨. PBS 완충액에 보관하며 4°C에서 안정적. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bacteria |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Mycobacterium tuberculosis Ag85b produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2915892 |
Product Specific Information
This antibody reacts with the Mycobacterium tuberculosis protein Ag85b (FbpB), which is a diacylglycerol acyltransferase/mycolyltransferase.
Target Information
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M. tuberculosis to murine alveolar macrophages (AMs).
They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor).
They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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