Thermo Fisher Scientific Mycobacterium tuberculosis CFP-10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-1 µg/mL

-

Product Specifications

Species Reactivity

Bacteria

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CFP10 (Rv3874) of Mycobacterium tuberculosis

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

15mM sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2915896

Product Specific Information

This antibody recognizes the CFP10 (Rv3874) protein of Mycobacterium tuberculosis and Mycobacterium bovis.

Western Blot: reducing conditions.

Target Information

Tuberculosis is a chronic bacterial infection which remains one of the leading killers of young adults world wide. Mycobacterium tuberculosis enters the alveoli by airborne transmission. They are engulfed by alveolar macrophages but resist destruction. Although the exact mechanism is not known, it is suspected that that Mycrobacterium tuberculosis survives by preventing the fusion of the phagosome and lysosome. As the bacterium accumulates it forms a tubercle, spreads to the lymph nodes and becomes a systemic infection. Although treatments for tuberculosis do exist, new strains of Mycobacterium tuberculosis that appear to have multiple-drug resistance (MDR) pose a considerable threat to public health.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.