Thermo Fisher Scientific TTLL12 Monoclonal Antibody (OTI4B2)
TTLL12 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, IHC, ICC, Flow Cytometry 등에 사용 가능. Human 및 Rat 반응성. Affinity Chromatography로 정제된 액상형 항체로, PBS/BSA/glycerol buffer에 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50 | – |
| Immunocytochemistry (ICC/IF) | 1:100 | – |
| Flow Cytometry (Flow) | 1:100 | – |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B2 |
| Immunogen | Full-length human recombinant TTLL12 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.73 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723743 |
Target Information
TTLL12 (Tubulin Tyrosine Ligase-Like Family, Member 12) is a 644 amino acid protein containing one TTL domain. Among the fourteen TTLL family members that modify tubulin, TTLL12 is the least characterized. It is highly expressed in multiple metastatic prostate cancer cell lines and is considered a potential target for tumor therapy. Overexpression of TTLL12 may alter chromosome ploidy, while downregulation affects several post-translational modifications of tubulin.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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