Thermo Fisher Scientific TTLL12 Monoclonal Antibody (OTI7F11)
TTLL12 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. Human, Dog, Rat 등 다양한 종에 반응. 고순도 Affinity Chromatography 정제 및 안정적 PBS/BSA/glycerol buffer 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F11 |
| Immunogen | Full length human recombinant protein of TTLL12 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.59 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723744 |
Target Information
TTLL12 (Tubulin Tyrosine Ligase-Like Family, Member 12) is a 644 amino acid protein containing one TTL domain. Among the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized. It is highly expressed in various metastatic prostate cancer cell lines and considered a potential target for tumor therapy. Overexpression of TTLL12 may alter chromosome ploidy, while downregulation influences several post-translational modifications of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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