Thermo Fisher Scientific FLT3 Polyclonal Antibody
FLT3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot과 ELISA에 적합합니다. 염소 유래 IgG 형태이며 비결합 상태로 제공됩니다. 인간 FLT3 외부 도메인 재조합 단백질로 면역화되었습니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific FLT3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.2 µg/mL |
| ELISA | 0.5–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified recombinant human FLT3 extracellular domain, expressed in mouse NSO cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1956922 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
FLT3 is a tyrosine protein kinase belonging to the growth factor receptor tyrosine kinase family. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, inducing homodimer formation in the plasma membrane and leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations causing constitutive activation of this receptor are associated with acute myeloid leukemia and acute lymphoblastic leukemia.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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