Thermo Fisher Scientific NFATC2 Polyclonal Antibody
Thermo Fisher Scientific의 NFATC2 Polyclonal Antibody는 인간 및 생쥐 시료에 반응하며, WB, ICC/IF, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 항체로, NFAT1(1–99aa) 영역에 대한 합성 펩타이드로 면역화되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA534940
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 1–99 of NFAT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2552289 |
Product Specific Information
- Recommended positive controls: HepG2, Juarkat, Raji, BCL-1, Raw264.7
- Predicted reactivity: Mouse (100%), Rat (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described:
- NFAT1 (also known as NFATp or NFATc2)
- NFAT2 (NFATc or NFATc1)
- NFAT3
- NFAT4 (NFATx or NFATc3)
These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1–4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors, and its subcellular localization is not calcineurin-dependent.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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