Thermo Fisher Scientific Phospho-delta Catenin (Tyr228) Monoclonal Antibody (M356)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

1:100

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

M356

Immunogen

Clone M356 was generated from a phospho-delta1-Catenin (Tyr-228) synthetic peptide containing amino acid residues around tyrosine 228 of human delta1-Catenin. This peptide sequence is highly conserved in rat and mouse delta1-Catenin.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Protein A

Storage buffer

PBS with 1mg/mL BSA, 50% glycerol

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2942619

Product Specific Information

The antibody detects a 110 kDa* protein corresponding to the molecular mass of delta1-Catenin on SDS-PAGE immunoblots of human A431 and HUVEC cells treated with pervanadate. This antibody does not detect this band after alkaline phosphatase treatment.

Target Information

Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.