Thermo Fisher Scientific PRMT4 Recombinant Rabbit Monoclonal Antibody (4Y3I1)
PRMT4/CARM1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, ELISA, Immunoprecipitation에 적합합니다. 높은 특이성과 재현성을 제공하며, 인간, 마우스, 랫트 시료에 반응합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Immunoprecipitation (IP)
- Tested Dilution: 0.5–4 µg antibody for 200–400 µg extracts
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4Y3I1 |
| Immunogen | Recombinant fusion protein containing amino acids 486–603 of human PRMT4/CARM1 (NP_954592.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094295 |
Product Specific Information
Immunogen sequence:
GSHYTSPSEN MWNTGSTYNL SSGMAVAGMP TAYDLSSVIA SGSSVGHNNL IPLANTGIVN HTHSRMGSIM STGIVQGSSG AQGSGGGSTS AHYAVNSQFT MGGPAISMAS PMSIPTNT
Target Information
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine.
Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation.
Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-51369_PRMT4_Q86X55-3_Rabbit.svg, MA5-51369_PRMT4_Q86X55-3_Rabbit_PDP.jpeg)
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