Thermo Fisher Scientific Lamin A/C Polyclonal Antibody
Lamin A/C 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 마우스에 반응합니다. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 적합합니다. 고순도 항원 친화 크로마토그래피 정제 제품으로 안정적 저장 가능.
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- PA578041
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- pk
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Thermo Fisher Scientific Lamin A/C Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:66–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Lamin A/C (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.27 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736076 |
Product Specific Information
- Positive Control: HeLa, NIH-3T3, C2C12
- Predicted Reactivity: Rat (89%), Dog (96%), Pig (96%), Rhesus Monkey (99%), Chimpanzee (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Lamins are intermediate filament proteins forming a matrix on the inner surface of the nuclear envelope. They exist as A, B, and C forms, with Lamins A and C being alternatively spliced products of the LMNA gene.
The LMNA gene is associated with several disorders including:
- Emery-Dreifuss muscular dystrophy
- Dunnigan-type familial partial lipodystrophy (FPLD)
- Limb-girdle muscular dystrophy (LGMD1B)
- Dilated cardiomyopathy (CMD1A)
- Axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1)
- Mandibuloacral dysplasia (MAD)
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
Usage Restriction
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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