Thermo Fisher Scientific Granzyme H Polyclonal Antibody
Human Granzyme H에 특이적인 Rabbit Polyclonal Antibody로 Western Blot과 IHC(Paraffin)에 적합함. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. NK 세포에서 발현되는 Granzyme H 단백질 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GZMH (Product #RP-88868) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790230 |
Product Specific Information
Immunogen sequence:
HPAYNPKNFS NDIMLLQLER KAKWTTAVRP LRLPSSKAQV KPGQLCSVAG WGYVSMSTLA TTLQEVLLTV QKDCQCERLF HGNYSRATEI CVGDPKKTQT GFKGDSGGPL VCKDVAQGIL SYGNKKGTPP GVYIKVSHFL PWIKRTM
Target Information
This gene encodes a member of the peptidase S1 family of serine proteases.
Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease.
This protein is reported to be constitutively expressed in NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells.
This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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