Thermo Fisher Scientific PPM1A Polyclonal Antibody
Human PPM1A 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 세포 스트레스 반응 및 종양 억제 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPM1A. Recombinant protein control fragment (Product #RP-98836). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790231 |
Product Specific Information
Immunogen sequence:
GQGNGLRYGL SSMQGWRVEM EDAHTAVIGL PSGLESWSFF AVYDGHAGSQ VAKYCCEHLL DHITNNQDFK GSAGAPSVEN VKNGIRTGFL EIDEHMRVMS EKKHGADRSG STAVGVLISP QHTYFINCGD SRGLLCRNRK VHFFTQDHKP SGAPHR
Target Information
PPM1A (Protein phosphatase 1A), also known as PPPM1A, belongs to the PP2C family. It is a serine/threonine protein phosphatase essential for regulating cellular stress responses in eukaryotes. PPM1A plays an important role in tumor suppression and negatively controls multiple signaling pathways critical for trophoblast invasion. The protein is distributed in both cytoplasm and nucleus of mammalian cells and has two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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