Thermo Fisher Scientific PON2 Polyclonal Antibody
Human PON2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 IHC(Paraffin)에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태이며, PBS/glycerol buffer에 보관. 세포 산화 스트레스 연구 및 항산화 관련 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PON2. Recombinant protein control fragment (Product #RP-93674). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.2) with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790226 |
Product Specific Information
Immunogen sequence:
ENSLLHLKTV KHELLPSVND ITAVGPAHFY ATNDHYFSDP FLKYLETYLN LHWANVVYYS PNEVKVVAEG FDSANGINIS PDDKYIYVAD ILAHEIHVLE KHTNMNLTQL KVLE
Target Information
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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