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Thermo Fisher Scientific Reticulon 1 Polyclonal Antibody
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Reticulon 1 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 IHC에 사용 가능. Rat 종에 반응하며, 합성 펩타이드 항원으로 제작. 동결건조 형태로 제공되며, 연구용으로만 사용.
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- pk
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마지막 업데이트 2025. 08. 04. 오전 06:31
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Thermo Fisher Scientific OSR00340W-100UL Reticulon 1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
563,100원VAT 포함 619,410원
Thermo Fisher Scientific · Thermo Fisher Scientific Reticulon 1 Polyclonal Antibody
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 200–250 of rat Reticulon 1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: RTN1.
Target Information
Reticulon-1 (formerly NSP, Neuroendocrine-Specific-Protein) is specifically expressed in neural and neuroendocrine tissues. The NSP gene is mapped to human chromosome 14q21–q22 and encodes three overlapping proteins: reticulon-1A (NSP-A), reticulon-1B (NSP-B), and reticulon-1C (NSP-C).
These proteins are anchored to endoplasmic reticulum membranes via their common C-terminal regions.
- Reticulon-1A: ~135 kDa, occurs in various isoforms depending on phosphorylation of serine residues. Reliable marker for neuroendocrine differentiation in lung cancer diagnosis (SCLC and carcinoid tumors).
- Reticulon-1B: ~45 kDa phosphoprotein, restricted to lung cancer cell line NCI-H82, not found in human tissues.
- Reticulon-1C: ~23 kDa, non-phosphorylated, found with Reticulon-1A in SCLC cell lines, absent in non-SCLC cultures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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