Thermo Fisher Scientific RIM1 Polyclonal Antibody
RIM1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB 및 IHC에 적합하며, 인간 시료 반응성. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적 유지. 신경전달 및 시냅스 기능 연구에 활용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminal region of human Rab3-interacting molecule 1 (RIMS1, RIM1) conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: RIM1
Target Information
Rims1 is a member of the RAS gene superfamily that regulates synaptic vesicle exocytosis and voltage-gated calcium channels during neurotransmitter and insulin release.
Mutations in Rims1 are associated with cone-rod dystrophy type 7 and may affect cognition.
Rims1 functions as a scaffold protein regulating neurotransmitter release at the active zone and maintaining normal release probability during short-term synaptic plasticity.
It also plays a role in dendrite formation by melanocytes. Multiple transcript variants encoding different isoforms have been described for Rims1.
Diseases associated with RIMS1 include Cone-Rod Dystrophy 7 and Retinitis Pigmentosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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