Thermo Fisher Scientific DOK4 Polyclonal Antibody
Rabbit polyclonal antibody against human DOK4 protein. Validated for WB and IHC applications. Provides reliable detection in RET-mediated signaling studies. Predicted cross-reactivity with mouse. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 228–258 amino acids from the C-terminal region of human DOK4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2095226 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
DOK proteins are enzymatically inert adaptor or scaffolding proteins that provide a docking platform for multimolecular signaling complexes.
DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway.
It may be involved in the regulation of the immune response induced by T-cells.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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