Thermo Fisher Scientific PTPRS Polyclonal Antibody
Human PTPRS 단백질을 인식하는 Goat Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합. 항원 친화 크로마토그래피로 정제된 Lyophilized 형태. 낮은 교차 반응성과 안정적인 저장 성능 제공.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PTPRS Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5–15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human PTP sigma / PTPRS (Glu30–Gly1260) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607944 |
Product Specific Information
This antibody detects the endogenous cleaved extracellular domain of human PTP sigma / PTPRS in Western blots.
In Western blots, less than 1% cross-reactivity with recombinant human LAR, PTPR beta, PTPR gamma, PTPR mu, or PTPR kappa is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
PTPRS is a cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans.
Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth.
Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection.
Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2.
Required for normal brain development, especially for normal development of the pituitary gland and the olfactory bulb.
Functions as a tyrosine phosphatase and mediates dephosphorylation of NTRK1, NTRK2, and NTRK3.
Plays a role in down-regulation of signaling cascades that lead to the activation of Akt and MAP kinases.
Down-regulates TLR9-mediated activation of NF-kappa-B, as well as production of TNF, interferon alpha, and interferon beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.