Thermo Fisher Scientific GRID2 Polyclonal Antibody
GRID2 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 사람, 생쥐, 랫드 반응성이 있으며 동결건조 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 시약입니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GRID2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 850–900 of human GRID2 conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: GRID2.
Target Information
GRID2 is a member of the ionotropic glutamate receptor family, which are predominant excitatory neurotransmitter receptors in the mammalian brain.
This multi-pass membrane protein is selectively expressed in cerebellar Purkinje cells.
A point mutation in the mouse ortholog, associated with the “lurcher” phenotype, leads to ataxia due to apoptosis of Purkinje cells during postnatal development.
Homozygous mutations cause embryonic lethality with neuronal loss in mid- and hindbrain regions.
GRID2 also contributes to synapse organization between parallel fibers and Purkinje cells.
Alternative splicing produces multiple isoforms, and mutations in this gene are linked to cerebellar ataxia in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.