Thermo Fisher Scientific LETM1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW) depending on sample size.
The antibody is supplied as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and store at -20°C.
Avoid multiple freeze/thaw cycles.
Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

The LETM1 gene encodes a protein localized to the inner mitochondrial membrane.
This protein maintains mitochondrial tubular shape and is essential for normal mitochondrial morphology and cellular viability.
Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome resulting from deletions on the distal short arm of chromosome 4.
Related pseudogenes exist on chromosomes 8, 15, and 19.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.