Thermo Fisher Scientific Cortisol Humanized Recombinant Human Monoclonal Antibody (SAA1437)
인간화된 재조합 코르티솔 단일클론 항체로 ELISA에 적합. CHO 세포에서 발현된 Human/VHH-hFc 형식. 3 mg/mL 농도의 액상 제품으로 Protein A/G로 정제. 연구용으로 코르티솔 검출 및 면역학적 분석에 활용 가능.
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Thermo Fisher Scientific Cortisol Humanized Recombinant Human Monoclonal Antibody (SAA1437)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Human / VHH-hFc |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1437 |
| Immunogen | Cortisol-KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Cortisol is the most potent glucocorticoid produced by the human adrenal gland. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH), which is regulated by corticotropin releasing factor (CRF).
ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop.
In plasma, a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin).
Cortisol acts through specific intracellular receptors and affects numerous physiological systems, including immune function, glucose counter-regulation, vascular tone, and bone metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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