Thermo Fisher Scientific COX4/COX4I2 Polyclonal Antibody
COX4 및 COX4I2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot과 IHC에 사용 가능. 합성 펩타이드 항원으로 제작되어 높은 특이성과 재현성을 제공. 연구용으로 미토콘드리아 전자전달계 관련 단백질 분석에 적합.
- 카탈로그번호
- OSC00167W-150UL
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous PubMed (Misc)
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 130–169 of human COX4 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 150 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: COX4 and COX4I2.
Target Information
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes.
The mitochondrially encoded subunits function in electron transfer, and the nuclear encoded subunits may be involved in the regulation and assembly of the complex.
This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation.
[provided by RefSeq, Jul 2008]
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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