Thermo Fisher Scientific NFS1 Monoclonal Antibody (OTI5D1), TrueMAB
인간 NFS1 단백질을 인식하는 단클론 항체로 Western blot 및 IHC(P) 분석에 적합합니다. 마우스 IgG2a 아이소타입이며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–299 of human NFS1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NFS1 (nitrogen fixation 1), also known as NIFS or IscS (cysteine desulfurase), is a member of the class V pyridoxal-phosphate-dependent aminotransferase family. It localizes to the cytoplasm or mitochondrion depending on cytosolic pH. The highest expression levels are found in heart and skeletal muscle, with lower levels in liver, brain, and pancreas. NFS1 catalyzes the removal of sulfur from cysteine to form alanine, supplying inorganic sulfur for iron-sulfur (Fe-S) clusters. These clusters are essential cofactors in electron transfer, enzymatic catalysis, and DNA repair processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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