Thermo Fisher Scientific ADAMTS1 Monoclonal Antibody (OTI4F3), TrueMAB
인간 ADAMTS1 단백질(aa 412-644)에 특이적인 Mouse IgG1 단클론 항체. Western blot에 사용 가능하며, 무보존제·동결건조 형태로 제공. 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F3 |
| Immunogen | Human recombinant protein fragment (aa 412–644 of human ADAMTS1, produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ADAMTS-1 belongs to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family.
Members share common modules such as:
- Propeptide region
- Metalloproteinase domain
- Disintegrin-like domain
- Thrombospondin type 1 (TS) motif
ADAMTS-1 contains two disintegrin loops and three C-terminal TS motifs, exhibiting anti-angiogenic activity.
Expression may be linked to inflammatory processes and cancer cachexia, and is likely necessary for normal growth, fertility, and organ morphology/function.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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