Thermo Fisher Scientific PXN Monoclonal Antibody (OTI2B8), TrueMAB
PXN 단백질을 인식하는 OTI2B8 클론의 Mouse IgG1 단일클론 항체. Western blot에 최적화된 TrueMAB 형식. 인간, 생쥐, 랫트 반응성. Lyophilized 형태로 제공되며 PBS/trehalose buffer에 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B8 |
| Immunogen | Full length human recombinant protein of human PXN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. Its tyrosine phosphorylation is influenced by changes in cell-cell adhesion. Paxillin associates with FAK and Crk through its SH2 domain, independently of the extracellular matrix. Initially discovered in fibroblasts, paxillin phosphorylation may also play roles during neurite extension in differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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