Thermo Fisher Scientific Epiregulin Polyclonal Antibody
Epiregulin 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, Flow Cytometry 등에 사용 가능. Human 시료 반응성 확인됨. KLH-conjugated EREG C-terminal peptide로 면역화. Protein A 및 항원 친화 크로마토그래피로 정제된 고순도 항체.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 | - |
| Flow Cytometry (Flow) | 1:10–1:50 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between amino acids 137–165 from the C-terminal region of human EREG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2542227 |
Target Information
Epiregulin (EREG) is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not to ErbB2 or ErbB3. It is primarily expressed in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney, and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts, and vascular smooth muscle cells, while inhibiting the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to yield a 6 kDa mature secreted form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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