Thermo Fisher Scientific Paxillin Polyclonal Antibody
Paxillin 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태이며 안정적인 PBS 버퍼에 저장됩니다.
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Thermo Fisher Scientific Paxillin Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encoding amino acids 356–558 of human Paxillin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Hela, Breast Ca
- Cellular location: Cytoplasmic
Target Information
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is influenced by conditions that alter cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain, independently of the extracellular matrix. Initially discovered in fibroblasts, paxillin phosphorylation may also play a role in neurite extension during differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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