Thermo Fisher Scientific IL34 Monoclonal Antibody (OTI5E1), TrueMAB
IL34 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot과 IHC(Paraffin)에 최적화되어 있습니다. Human 시료 반응성이 있으며, 고순도의 Affinity chromatography 정제 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 77–242 of human IL34 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor (CSF-1R, CD115), which is shared with M-CSF. Although IL-34 has no amino acid sequence homology to M-CSF, they exhibit similarities in secondary structure and overlapping functions. IL-34 promotes myeloid survival, proliferation, and differentiation, and plays a role in osteoclast formation. Its expression is detected in various tissues and is most abundant in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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