Thermo Fisher Scientific DcTRAILR1 Polyclonal Antibody
Mouse DcTRAILR1 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며 단백질 발현 분석에 사용. Protein G로 정제된 액상 항체로, 4°C 단기 보관 및 -20°C 장기 보관 권장.
- 카탈로그번호
- PA129849
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 155–168 (CSSSVSNPRNWLFL) of mouse DcTRAILR1; GenBank no: NP_077252.2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.2% gelatin |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2207071 |
Product Specific Information
PA1-29849 detects DcTRAILR1 from mouse samples.
Target Information
Mouse DcTRAILR1 and DcTRAILR2 (decoy TRAIL receptors 1 and 2) are receptors for TRAIL according to ligand-receptor binding assays (Schneider et al., 2001). However, overexpression does not cause NF-κB activation or apoptosis, as would be expected of a TRAIL receptor. These receptors are therefore referred to as decoys.
Cells expressing decoy TRAIL receptors at high levels relative to actual TRAIL receptors may use them as protection against the cytotoxic action of TRAIL (Bouralexis et al., 2005). Further analysis of these murine TRAIL decoy receptors will aid in understanding the complex biology underlying TRAIL ligand/receptor interactions.
DcTRAILR1: 176 amino acids (GenBank no: NP_077252.2)
DcTRAILR2: 198 amino acids (GenBank no: AAN87807.1)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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