Thermo Fisher Scientific MEK2 Polyclonal Antibody
Rabbit polyclonal antibody against human MEK2. Validated for Western blot at 1–3 µg/mL. Detects MEK2 involved in MAPK/ERK signaling. Supplied as liquid at 0.5 mg/mL, stored at 4°C short term or -20°C long term. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (Human) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1958334 |
Product Specific Information
PA1-29852 detects MEK2 from human samples.
Target Information
MAP2K2 (MEK2) is a dual specificity serine/threonine kinase that plays a critical role in mitogen growth factor signal transduction. MEK2 (also known as MAPKK2) belongs to a family of tyrosine/threonine kinases that activate ERK1/2 and MAPK enzymes by phosphorylating residues within the TEY motif in the activation loop.
MEK1 and MEK2 are activated by dual phosphorylation on serine 218 and 222. Threonine 292 of MEK1 is phosphorylated by ERK2, providing a negative feedback mechanism to suppress MEK1 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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